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Bioinformatics Manager

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Location: Wauwatosa WI

Company Name: Medical College of Wisconsin

Occupational Category: 19-1042.00,Medical Scientists, Except Epidemiologists

Date Posted: 2020-02-10

Valid Through: 2020-03-11

Employment Type: FULL_TIME


Position Description:


The Genomic Sciences and Precision Medicine Center (GSPMC) is pioneering team science and dedicated to advancing research in genomics and epigenomics. The Mission of the GSPMC is help prevent, diagnose, and treat diseases, as well as improve the wellness of our patients and the community through scientific investigations and their rapid translation to the medical practice. Our Vision is to move “beyond the base pairs” in order to better interpret genomics data, leading to more precise healthcare. Within the GSPMC, the Bioinformatics and Data Analytic Unit (BDAU) is responsible for the service lines that underly a diverse portfolio of clinical and research projects. Members of the BDAU team, therefore, participate in a combination of service line (clearly defined deliverable and timeline) and research activities.

The Bioinformatics manager will oversee the day-to-day operations of the BDAU. They will be responsible for managing the team’s project portfolio consisting of service line, research, and developmental projects. Because translational research is critical for GSPMC, the Manager must be capable of maintaining the defined timelines of the Service Lines, while also facilitating the team to implement a research project portfolio. The Manager will participate in decision making and strategic planning regarding the technology and products offered by GSPMC. The Manager and Bioinformatics Director will collaborate with GSPMC Administrative, Laboratory Sciences, Medical, and Commercialization leaders, to define new service offerings and to refine the use of existing services.

The successful candidate will have experience managing a data analytic team, be well-versed in a breadth of scientific and informatic methods, be able to translate the GSPMC Mission and Vision into bioinformatic products and bring knowledge for how to construct continuous professional development (CPD) to advance the capabilities of individual team members.

Primary Functions
• Establish operating procedures for the BDAU; formulate plans to facilitate the accomplishment of assigned responsibilities and organize activities to achieve the desired levels of productivity and quality for standardized bioinformatic and analytic services.
• Formulate Statements of Work (SoW) for specific projects and opportunities
• Facilitate IT operations within GSPMC through collaboration with our Research Computing manager to resolve issues and, when needed, elevate concerns to leadership.
• Provide policy interpretation, guidance and direction to employees and develop and communicate Center operating policies and procedures as it relates to bioinformatic technologies.
• Work with Director of Lab Outreach, Associate Director of Bioinformatics, and Chief Medical Officer to create a development schedule to onboard new services and offerings for the service lines.
• Keep up to date on bioinformatics, technology, and industry knowledge related to role and disseminate to staff and Center leadership.
• Train staff in bioinformatics processes and methods or work with staff to establish an appropriate CPD plan
• Leads the BDAU team in, or, if necessary, directly performs, validation of new procedures, protocols, software, and translational medicine projects.
• Leads the BDAU team in, or, if necessary, directly performs, troubleshooting of issues in bioinformatics pipelines
• Leads the BDAU team in, or, if necessary, directly performs bioinformatics analysis on research or clinical samples to meet deadlines defined in SoW.
• Interpret analyzed data including development of novel analysis methodology and visualizations which will extend the research and clinical offerings of the Center

Preferred Schedule:

Position Requirements:


Appropriate education and/or experience may be substituted on equivalent basis

Minimum Required Education: Master’s degree, PhD preferred.

Minimum Required Experience: 8 years

Knowledge – Skills – Abilities

Excellent time management skills. Excellent organizational skills. Management experience related to bioinformatics preferred. Deep cross-disciplinary and analytical skills and broad experience using computational methods, databases, software, and hardware are required, including experience with bioinformatics tools and algorithms on large-scale data. Requires extensive experience in copy number variance, Whole Exome, Whole Genome, and RNAseq. Experience with ChIPseq, ATACseq, Microbiome, Single Cell, or Liquid Biopsy a plus.

Strong project management and excellent oral and written communication skills are essential to this role. Ability to navigate a complex organizational structure, independently seek resources, and act proactively and strategically in the spirit of collaboration, partnership, and problem solving.

About MCW

The Medical College of Wisconsin (MCW) is one of the largest healthcare employers in Wisconsin. We are a distinguished leader and innovator in the education and development of the next generation of physicians, scientists, pharmacists and health professionals; we discover and translate new knowledge in the biomedical and health sciences; we provide cutting-edge, collaborative patient care of the highest quality; and we improve the health of the communities we serve.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class